Sodium-glucose co-transporter type 2 (SGLT2)selective reversible inhibitor(inhibition constant (Ki)-0.55 nmol).SGLT2 is selectively expressed in the kidneys and is not found in more than 70 other body tissues (including liver, skeletal muscle, adipose tissue, breast, bladder and brain).SGLT2 is the main carrier involved in renal tubular glucose reabsorption.